RaymondJHutchinsonMD

Pediatric Hematology & Oncology • Ann Arbor, MI

Pediatric Hematologic Oncology

Active Emeritus Professor of Pediatrics, University of Michigan Medical School

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Office
1301 Catherine Street, Ann Arbor , Mi.
Rm 3109
Ann Arbor, MI 48109
Phone+1 734-647-1576

Fax+1 734-615-1390
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Education & Training

University of MichiganMS, Clinical trial design and statistical analysis, 1988 - 1989
Children's Hospital of PhiladelphiaFellowship, Pediatric Hematology/Oncology, 1975 - 1978
Tufts Medical CenterResidency, Pediatrics, 1973 - 1975
Harvard Medical SchoolClass of 1973

Certifications & Licensure

MI State Medical License 1978 - 2027
PA State Medical License 1975 - 1978
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors Start of enrollment: 2004 Mar 25
Recruiting
Study of Rituximab Plus High-Dose Chemotherapy Poor Prognosis Non-Hodgkin's Lymphoma Start of enrollment: 2003 Mar 01
Terminated
Phase 2
Study of Rituximab Plus High-Dose Chemotherapy Non-Hodgkin's Lymphoma Start of enrollment: 2001 Apr 01
Completed
Phase 2
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL Start of enrollment: 2010 Jun 01
Terminated
Phase 1, Phase 2
Childhood Cancer Survivor Study Start of enrollment: 1995 Jan 05
Recruiting
Roles: Principal Investigator, Contact
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
A Study Of Panobinostat In Children With Refractory Hematologic Malignancies Start of enrollment: 2011 Mar 01
Completed
Phase 1
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
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Publications & Presentations

PubMed

Comparing internal versus external carotid artery branch delivery of intraarterial chemotherapy for the treatment of retinoblastoma.
Yunshu Zhou, David Musch, Amy Edmonds, Laura Sedig, Raymond Hutchinson, Neeraj Chaudhary, Hakan Demirci, Chang, E.> ;Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2023 Sep 1
6 citations
Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR).
James A Whitlock, Jemily Malvar, Luciano Dalla-Pozza, John M Goldberg, Lewis B Silverman, David S Ziegler, Andishe Attarbaschi, Patrick A Brown, Rebecca A Gardner, Pau...> ;Pediatric Blood & Cancer. 2022 Nov 1
19 citations
Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) c...
Pommert, L., Schafer, E., Malvar, J., Gossai, N., Florendo, E., Pulakanti, K., Heimbruch, K., Stelloh, C., Chi, Y., Sposto, R., Rao, S., Huynh, V., Brown, P., Chang, B...> ;American Journal of Hematology. 2022 May 1
8 citations
Temsirolimus combined with cyclophosphamide and etoposide for pediatric patients with relapsed/refractory acute lymphoblastic leukemia: a Therapeutic Advances in Child...
Sarah K Tasian, Lewis B Silverman, James A Whitlock, Richard Sposto, Joseph P Loftus, Eric S Schafer, Kirk R Schultz, Raymond J Hutchinson, Paul S Gaynon, Etan Orgel, ...> ;Haematologica. 2022 Oct 1
4 citations
Palliative care is not associated with decreased intensity of care: Results of a chart review from a large children's hospital.
Laura K Sedig, Jessica L. Spruit, Jessica Southwell, Trisha K. Paul, Melissa K. Cousino, Harlan McCaffery, Kenneth Pituch, Raymond J. Hutchinson> ;Pediatric Blood & Cancer. 2021 Oct 4
1 citations
Ethical Perspectives of Chinese and United States Physicians at Initiation of a Research Collaborative.
Christopher Grondin, Yali Cong, Nahid Keshavarzi, Michael E. Geisser, Joseph C. Kolars, Raymond J. Hutchinson> ;Accountability in Research. 2021 May 4
12 citations
Impact of Risk-Adapted Therapy for Pediatric Hodgkin Lymphoma on Risk of Long-Term Morbidity: A Report From the Childhood Cancer Survivor Study.
Kevin C. Oeffinger, Kayla Stratton, Melissa M. Hudson, Wendy M. Leisenring, Tara O. Henderson, Rebecca M. Howell, Suzanne L. Wolden, Louis S. Constine, Lisa Diller, Ch...> ;Journal of Clinical Oncology. 2021 Feb 25
A Therapeutic Conundrum: Should a Physician Serve Simultaneously as Caregiver and Researcher?
Raymond J. Hutchinson> ;The American Journal of Bioethics. 2020 Sep 18
22 citations
A Metabolomics Approach for Early Prediction of Vincristine-Induced Peripheral Neuropathy.
Parul Verma, Jayachandran Devaraj, Jodi L. Skiles, Tammy J. Sajdyk, Richard H. Ho, Raymond J. Hutchinson, Elizabeth Wells, Lang Li, Jamie L. Renbarger, Bruce A. Cooper...> ;Scientific Reports. 2020 Jun 15
11 citations
Experiences at the End of Life From the Perspective of Bereaved Parents: Results of a Qualitative Focus Group Study.
Laura K Sedig, Jessica L. Spruit, Trisha K. Paul, Melissa K. Cousino, Kenneth Pituch, Raymond J. Hutchinson> ;The American Journal of Hospice & Palliative Care. 2020 Jun 1
10 citations
Sharing Health Data and Biospecimens with Industry - A Principle-Driven, Practical Approach.
Kayte Spector-Bagdady, Raymond J. Hutchinson, Erin O. Kaleba, Sachin Kheterpal> ;The New England Journal of Medicine. 2020 May 27
6 citations
Supporting Pediatric Patients and Their Families at the End of Life: Perspectives From Bereaved Parents:
Laura K Sedig, Jessica L. Spruit, Trisha K. Paul, Melissa K. Cousino, Harlan McCaffery, Kenneth Pituch, Raymond J. Hutchinson> ;The American Journal of Hospice & Palliative Care. 2020 May 6
4 citations
18F-2-fluoro-2-deoxyglucose uptake in white adipose tissue on pediatric oncologic positron emission tomography (PET)/computed tomography (CT).
Ka Kit Wong, Laura K Sedig, David A. Bloom, Raymond J. Hutchinson, Barry L. Shulkin> ;Pediatric Radiology. 2020 Apr 1
1 citations
Fluorescein angiography findings in both eyes of a unilateral retinoblastoma case during intra-arterial chemotherapy with melphalan.
Cem Ozgonul, Neeraj Chaudhary, Raymond J. Hutchinson, Steven M. Archer, Hakan Demirci> ;International Journal of Ophthalmology. 2019 Dec 18
20 citations
Genetic Variants Associated With Vincristine-Induced Peripheral Neuropathy in Two Populations of Children With Acute Lymphoblastic Leukemia
Lang Li, Tammy J. Sajdyk, Ellen M. Lavoie Smith, Chien Wei Chang, Claire Li, Richard H. Ho, Raymond J. Hutchinson, Elizabeth Wells, Jodi L. Skiles, Naomi J. Winick, Pa...> ;Clinical Pharmacology and Therapeutics. 2019 Jun 1
22 citations
A single-center multidisciplinary approach to managing the global Erwinia asparaginase shortage
Bernard L. Marini, Julia Brown, Lydia L. Benitez, Emily Walling, Raymond J. Hutchinson, Rajen Mody, Rama Jasty Rao, Lynn Slagle, Lauren Bishop, Kristen Pettit, Dale L....> ;Leukemia & Lymphoma. 2019 May 17
2 citations
Do Deauville Scores Improve the Clinical Utility of End-of-Therapy FDG PET Scans for Pediatric Hodgkin Lymphoma?
Laura K Sedig, Jason J Bailey, Ka Kit Wong, Richard K.J. Brown, Mark S. Kaminski, Raymond J. Hutchinson> ;AJR. American Journal of Roentgenology. 2019 Feb 1
Redefining Informed Consent as Part of Consent Training in Pediatrics—Reply
Alan R. Tait, Raymond J. Hutchinson> ;JAMA Pediatrics. 2018 Jul 1
15 citations
Insurance, chronic health conditions, and utilization of primary and specialty outpatient services: a Childhood Cancer Survivor Study report
Emily L. Mueller, Elyse R. Park, Anne C. Kirchhoff, Karen Kuhlthau, Paul C. Nathan, Giselle K. Perez, Julia Rabin, Raymond J. Hutchinson, Kevin C. Oeffinger, Leslie L....> ;Journal of Cancer Survivorship. 2018 Jun 25
7 citations
Right now, in the right way: U. S. Food and Drug Administration's expanded access program and patient rights.
M. E. Blair Holbein, Kevin J. Weatherwax, Misty Gravelin, Raymond J. Hutchinson, George A. Mashour> ;Journal of Clinical and Translational Science. 2018 Jun 1
80 citations
Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study.
Weili Sun, Jemily Malvar, Richard Sposto, Anupam Verma, Jennifer J. Wilkes, Robyn M. Dennis, Kenneth Heym, Theodore W. Laetsch, Melissa Widener, Susan R. Rheingold, Ja...> ;Leukemia. 2018 Mar 15
12 citations
Informed Consent Training in Pediatrics-Are We Doing Enough?
Alan R. Tait, Raymond J. Hutchinson> ;JAMA Pediatrics. 2018 Mar 1
5 citations
Ethical, legal, and social implications of learning health systems.
Jodyn Platt, Kayte Spector-Bagdady, Tevah Platt, Raymond De Vries, Dorene S. Markel, Raymond J. Hutchinson, Frank J. Manion, Georgiann Ziegler, Joshua C. Rubin, Sharon...> ;Learning Health Systems. 2018 Jan 1
9 citations
Ataxia Telangiectasia and Cancer Predisposition: Challenges in Management.
Santhosh A. Upadhyaya, Rajen Mody, Kelly Walkovich, Raymond J. Hutchinson, John T. Sandlund, James A. Connelly> ;Journal of Pediatric Hematology/oncology. 2017 Dec 1
10 citations
Disclosing Study Information to Children and Adolescents: Is What They Want, What Their Parents Think They Want?
Alan R. Tait, Michael E. Geisser, Lamira Ray, Raymond J. Hutchinson, Terri Voepel-Lewis> ;Academic Pediatrics. 2017 Jun 10
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Grant Support

Childrens Cancer GroupNational Cancer Institute1997–2002
Effect Of Recipient Age /Graft VS Host Disease Post BMTNational Institute On Aging2001
Vaccine Therapy Of Pediatric Malignancies Utilizing Dendritic CellsNational Center For Research Resources1999–2000
Treatment Of Children With Lower Risk Leukemia Incorporating 6 ThioguanineNational Center For Research Resources1998–1999
Continuous 21 Day Infusion Of Topotecan In Children With Relapsed Solid TumorsNational Center For Research Resources1997–1999
B43-PAP Immunotoxin Combined With Standard 4 Drug Induction For CD+ AllNational Center For Research Resources1997–1999
Oral And IV Navelbine (VINORELBINE) In Pediatric Cancer PatientsNational Center For Research Resources1997
Continual Mercaptopurine Followed By Continual Cytosine Arabinoside In LeukemiaNational Center For Research Resources1997
A Pilot Trial Of 6 Thioguanine In Children LeukemiaNational Center For Research Resources1997
Treatment Of Newly Diagnosed Children With Low Risk LeukemiaNational Center For Research Resources1996
CCG 0936--Oral And Intravenous Navelbine In Pediatric Cancer PatientsNational Center For Research Resources1996
CCG 0932--Temozolomide In Pediatric And Adolescent Patients With CancerNational Center For Research Resources1996
CCG 0926--All Trans Retinoic Acid In Combination With Interferon Alpha2aNational Center For Research Resources1996
Cancer In ChildrenNational Cancer Institute1994–1996
Children'S Cancer Study GroupNational Cancer Institute1988–1993