RichardSVander HeideMD,Ph.D., MBA, FCAP

PubMed

• 5 citations
  Proteomic analysis of descending thoracic aorta identifies unique and universal signatures of aneurysm and dissection.
  Louis Saddic, Amanda Orosco, Dongchuan Guo, Dianna M Milewicz, Dana Troxlair, Richard Vander Heide, David Herrington, Yue Wang, Ali Azizzadeh, Sarah J Parker> ;JVS-Vascular Science. 2022 Jan 1
• 1 citations
  ACE2 Chromogenic Immunostaining Protocol Optimized for Formalin-fixed Paraffin Embedded Human Tissue Sections.
  Marda Jorgensen, Paul N. Joseph, Amanda L. Posgai, Richard S. Vander Heide, Irina Kusmartseva, Mark A. Atkinson> ;STAR Protocols. 2021 Jul 21
• 33 citations
  Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells.
  Matthew J. Dean, Juan B. Ochoa, Maria Dulfary Sanchez-Pino, Jovanny Zabaleta, Jone Garai, Luis Del Valle, Dorota Wyczechowska, Lyndsey Buckner Baiamonte, Phaethon Phil...> ;Frontiers in Immunology. 2021 Jul 14
• 47 citations
  Posttraumatic Stress Disorder and Cardiovascular Disease: State of the Science, Knowledge Gaps, and Research Opportunities
  Christopher J. O'Donnell, Lisa Schwartz Longacre, Beth E. Cohen, Zahi A. Fayad, Charles F. Gillespie, Israel Liberzon, Gita A. Pathak, Renato Polimanti, Victoria B. Ri...> ;JAMA Cardiology. 2021 Oct 1
• 27 citations
  SARS-CoV-2 infection of the pancreas promotes thrombofibrosis and is associated with new-onset diabetes.
  Mirza Muhammad Fahd Qadir, Manika Bhondeley, Wandy L. Beatty, Dina Gaupp, Lara A. Doyle-Meyers, Tracy Fischer, Ishitri Bandyopadhyay, Robert V Blair, Rudolf P. Bohm, J...> ;JCI Insight. 2021 Aug 26
• 57 citations
  Endothelial cell infection and dysfunction, immune activation in severe COVID-19.
  Zhongnan Qin, Fengming Liu, Robert V Blair, Chenxiao Wang, Haoran Yang, Joseph Mudd, Joshua M Currey, Naoki Iwanaga, Jibao He, Ren Mi, Kun Han, Cecily C. Midkiff, Moha...> ;Theranostics. 2021 Jul 6
• 89 citations
  SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro .
  Fengming Liu, Kun Han, Robert V Blair, Kornelia Kenst, Zhongnan Qin, Berin Upcin, Philipp Wörsdörfer, Cecily C. Midkiff, Joseph Mudd, Elizaveta Belyaeva, Nicholas S Mi...> ;Frontiers in Cellular and Infection Microbiology. 2021 Jul 6
• 42 citations
  COVID-19 myocarditis: quantitative analysis of the inflammatory infiltrate and a proposed mechanism.
  Sharon E. Fox, Lacey Falgout, Richard S. Vander Heide> ;Cardiovascular Pathology. 2021 Jun 24
• 13 citations
  Transcriptome and Functions of Granulocytic Myeloid-Derived Suppressor Cells Determine their Association with Disease Severity of COVID-19
  Matthew J. Dean, Juan B. Ochoa, Maria Dulfary Sanchez-Pino, Jovanny Zabaleta, Jone Garai, Luis Del Valle, Dorota Wyczechowska, Lyndsey R. Buckner, Phaethon Philbrook, ...> ;Medrxiv. 2021 Mar 29
• 1 citations
  Unusual complication of late presentation deceleration aortic injury.
  William Risher, Samuel Stevenson, Raman Danrad, Edmund K. Kerut, Robert Batson, Ritu Bhalla, Richard S. Vander Heide, Larry H. Hollier> ;Echocardiography. 2021 Mar 16
• 7 citations
  COVID-19: The Heart of the Matter-Pathological Changes and a Proposed Mechanism.
  Sharon E. Fox, Richard S. Vander Heide> ;Journal of Cardiovascular Pharmacology and Therapeutics. 2021 Mar 11
• 182 citations
  Myocarditis is rare in COVID-19 autopsies: cardiovascular findings across 277 postmortem examinations.
  Marc K. Halushka, Richard S. Vander Heide> ;Cardiovascular Pathology. 2021 Jan 1
• 111 citations
  Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19.
  Irina Kusmartseva, Wenting Wu, Farooq Syed, Verena van der Heide, Marda Jorgensen, Paul N. Joseph, Tang X, Eduardo Candelario-Jalil, Changjun Yang, Harry S. Nick, Jack...> ;Cell Metabolism. 2020 Dec 1
• 6 citations
  Coronavirus Disease 2019 Autopsies and Personal Protective Equipment.
  Bing Han, Ritu Bhalla, Fernanda da Silva Lameira, Richard S. Vander Heide, Gordon L. Love> ;Archives of Pathology & Laboratory Medicine. 2020 Nov 1
• 117 citations
  Unexpected Features of Cardiac Pathology in COVID-19 Infection.
  Sharon E. Fox, Guang Li, Aibek Akmatbekov, Jack L. Harbert, Fernanda S. Lameira, J. Quincy Brown, Richard S. Vander Heide> ;Circulation. 2020 Sep 15
• 77 citations
  Cardiac Endotheliitis and Multisystem Inflammatory Syndrome After COVID-19.
  Sharon E. Fox, Fernanda S. Lameira, Elizabeth B Rinker, Richard S. Vander Heide> ;Annals of Internal Medicine. 2020 Jul 29
• 827 citations
  Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans.
  Sharon E. Fox, Aibek Akmatbekov, Jack L. Harbert, Guang Li, J. Quincy Brown, Richard S. Vander Heide> ;The Lancet. Respiratory Medicine. 2020 Jul 1
• 12 citations
  Identification of Putative Early Atherosclerosis Biomarkers by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes.
  Sarah J. Parker, Lulu Chen, Weston R. Spivia, Georgia Saylor, Chunhong Mao, Vidya Venkatraman, Ronald J. Holewinski, Mitra Mastali, Rakhi Pandey, Grace Athas, Guoqiang...> ;Journal of Proteome Research. 2020 Mar 23
• 74 citations
  Proteomic Architecture of Human Coronary and Aortic Atherosclerosis.
  David M. Herrington, Chunhong Mao, Sarah J. Parker, Zongming Fu, Guoqiang Yu, Lulu Chen, Vidya Venkatraman, Yi Fu, Yizhi Wang, Timothy D. Howard, Goo Jun, Caroline F. ...> ;Circulation. 2018 Jun 19
• 12 citations
  Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons.
  James E. Hixson, Goo Jun, Lawrence C. Shimmin, Yizhi Wang, Guoqiang Yu, Chunhong Mao, Andrew S. Warren, Timothy D. Howard, Richard S. Vander Heide, Jennifer E. Van Eyk...> ;Scientific Reports. 2017 Jun 22
• 9 citations
  Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis.
  Chunhong Mao, Timothy D. Howard, Daniel E. Sullivan, Zongming Fu, Guoqiang Yu, Sarah J. Parker, Rebecca Will, Richard S. Vander Heide, Yue Wang, James E. Hixson, Jenni...> ;Journal of Proteomics and Genomics Research. 2017 Mar 4
• 36 citations
  Pathobiology of Ischemic Heart Disease: Past, Present and Future
  L. Maximilian Buja, Richard S. Vander Heide> ;Cardiovascular Pathology. 2016 May 1
• 2 citations
  Mending a Broken Heart: The Role of Sarcospan in Duchenne Muscular Dystrophy–Associated Cardiomyopathy
  Richard S. Vander Heide> ;Journal of the American Heart Association. 2015 Dec 23
• 45 citations
  Novel therapeutic strategies for ischemic heart disease
  Adam J. Perricone, Richard S. Vander Heide> ;Pharmacological Research. 2014 Nov 1
• 12 citations
  Conditional Knockout of Myocyte Focal Adhesion Kinase Abrogates Ischemic Preconditioning in Adult Murine Hearts
  Adam J. Perricone, Benjamin J. Bivona, Fannie R. Jackson, Richard S. Vander Heide> ;Journal of the American Heart Association. 2013 Sep 30
• Join now to see all

Journal Articles

• Conditional knockout of myocytes focal adhesion kinase abrogates ischemia preconditioning in adult murine hearts  
  Perricone AJ, Bivona, BJ, Jackson F, Vander Heide RS, JAHA, 9/30/2013
• Cardioprotection and Myocardial Reperfusion: Pitfalls to Clinical Application  
  Vander Heide RS, Steenbergen C, Circ Res, 1/1/2013
• Effect of hypothermia on doxorubicin-induced cardiac myoblast signaling and cell death  
  L'Ecuyer T, Aggarwal S, Zhang JP, Vander Heide RS, Cardiovasc Path, 1/1/2012
• Clinically useful cardioprotection: ischemic preconditioning then and now  
  Vander Heide RS, J Cardiovasc Pharm Ther, 1/1/2011
• Regional expression of HOXA4 along the aorta and its potential role in human abdominal aortic aneurysm  
  Lillvis JH, Erdman R, Schworer CM, Golden A, Derr K, Gatalica Z, Cox LA, Shen J, Vander Heide RS, Lenk GM, Hlavaty L, Li L, Elmore JR, Franklin DP, Gray JL, Garvin ..., BMC Physiology, 1/1/2011
• Targeted intracellular delivery of catalase protects neonatal rat ventricular myocytes against hypoxia/reoxygenation and ischemia/reperfusion injury  
  Undyala V, Terlecky SR, Vander Heide RS, Cardiovasc Path, 1/1/2011
• Ischemic preconditioning activates focal adhesion kinase-Akt survival signaling pathway in Langendorff perfused rat hearts  
  Wei, H, Vander Heide RS, Am J Physiol Heart Circ Physiol, 1/1/2010
• TGF-b stimulates intestinal epithelial FAK synthesis via Smad- and p38-dependent mechanisms  
  Walsh MF, Ampasala DR, Hatfield J, Vander Heide R, Rishi AK, Basson MD, Am J Path, 8/1/2008
• Heat stress activates AKT via focal adhesion kinase mediated pathway in neonatal rat ventricular myocytes  
  Wei H, Vander Heide RS, Am J Physiol Heart Circ Physiol, 1/1/2008
• Molecular basis of adriamycin-induced cardiotoxicity  
  Vander Heide RS, L'Ecuyer T, Heart and Metabolism, 1/1/2007
• DNA damage is an early event in doxorubicin-induced cardiomyocyte death  
  L'Ecuyer T, Sanjeev S, Thomas R, Das L, Campbell W, Novak R, Vander Heide RS, Am J Physiol Heart Circ Physiol, 1/1/2006
• Focal adhesion kinase protein levels in gut epithelial motility  
  Basson MD, Sanders MA, Gomez R, Hatfield J, Vander Heide RS, Thamilselvan V, Zhang J, and Walsh MF, Am J Physiol Gastrointest Liver Physiol, 1/1/2006
• Glutathione-S-transferase overexpression protects against anthracycline-induced H9C2 cell death  
  L'Ecuyer T, Allebban Z, Thomas R, and Vander Heide RS, Am J Physiol Heart Circ Physiol, 1/1/2004
• Effect of Increased expression of cytoskeletal protein vinculin on ischemia-reperfusion injury in ventricular myocytes  
  Wei H, L'Ecuyer T, Vander Heide RS, Am J of Physiol, 1/1/2003
• Aqueous oxygen attenuation of reperfusion microvascular ischemia in a canine model of myocardial infarction  
  Spears JR, Prcevski P, Xu R, Li L, Brerton G, Di Carli M, Spanta A, Crilly R, Lavine S, and Vander Heide RS, ASAIO Journal, 1/1/2003
• Increased expression of a small heat shock protein (HSP27) protects adult canine ventricular myocytes from simulated ischemia/reperfusion injury  
  Vander Heide RS, Am J of Physiol, 1/1/2002
• Aqueous oxygen hyperbaric reperfusion in a porcine model of myocardial infarction  
  Spears JR, Henney C, Prcevski P, Xu R, Li L, Brereton G, Di Carli M, Spanta A, Crilly R, Sulaiman AM, Hadeed S, Lavine S, Patterson WR, Creech J, and Vander Heide RS, J Invas Cardiol, 1/1/2002
• Cytomegalovirus disease in non-conventional hosts (non-AIDS/non-transplant patients)  
  Kanno M, Chandrasekar PH, Bentley G, Vander Heide RS, Alangaden GJ, Clinical Infectious Diseases, 1/1/2001
• Anthracycline-induced cardiac injury using a cardiac cell line: potential for gene therapy studies  
  L'Ecuyer TL, Horenstein MS, Thomas R, Vander Heide RS, Mol Gen and Metabolism, 1/1/2001
• Myocardial blood flow, function and metabolism in repetitive stunning  
  Di Carli M, Precevski P, Singh TP, Leonen M, Muzik O, Vander Heide RS, J Nucl Med, 1/1/2000
• Percutaneous pulmonary artery gene transfer using naked plasmid DNA delivered via angioplasty  
  Keller L, Vander Heide RS, Pebbles KA, L'Ecuyer TJ, Pediatr Cardiol, 1/1/2000
• Pulmonary edema complicating prostacyclin therapy for pulmonary hypertension associated with scleroderma: A case of capillary hemangiomatosis associated with sclerod...  
  Gugnani MK, Pierson C, Vander Heide RS, Girgis R, Arthritis Rheum, 1/1/2000
• The molecular basis of anthracycline-induced cardiotoxicity and its prevention  
  Horenstein M.S., Vander Heide RS, L'Ecuyer T, Mol Gen and Metabolism, 1/1/2000
• Skeletal muscle ventricles: full versus half aortic ligation  
  Greer K, Lu H, Hammond R, Bastian S, Vander Heide RS, Stephenson L, J Card Surg, 1/1/1998
• Causes of isolated aortic insufficiency in an urban population in the 1990's  
  Hlavaty LA, Vander Heide RS, Cardiovasc Pathol, 1/1/1998
• Join now to see all

Books/Book Chapters

• Pathobiology of Ocular Disease 
  Chapter: Chapter 1: The Cell in Health and Disease 
  Page 1 - 28Vander Heide RSEditors: Klintworth G, Garner A.Informa Healthcare PublishersEdition 3rd,2008
• Purines and Myocardial Protection 
  Chapter: ATP metabolism and ischemic preconditioning 
  Page 433 - 445Reimer KA, Vander Heide RS, Jennings RBEditors: Abd-Elfattah A, Wexler A, Norwell MA.Kluwer Academic Publishers1996
• Ischemic Preconditioning; The Concept of Endogenous Cardioprotection 
  Chapter: Role of altered energy metabolism in ischemic preconditioning 
  Page 75 - 103Reimer KA, Vander Heide RS, Murry CE, Jennings RBEditors: Przyklenk K, Kloner RA, and Yellon DM, Norwell MA.Kluwer Academic Publishers1994
• Pathophysiology of Severe Ischemic Myocardial Injury 
  Chapter: Importance of Mechanical Factors in Ischemia and Reperfusion Injury 
  Page 337 - 355Ganote CE, Vander Heide RSEditors: Piper HM.Kluwer Academic Publishers, BV Dordrecht, The Netherlands1989
• Reperfusion and Revascularization in Acute Myocardial Infarction 
  Chapter: The No-Reflow Phenomenon 
  Ganote CE, Vander Heide RSEditors: Schettler, et al.Springer-Verlag, Berlin/Heidelberg, Germany1988
• Join now to see all

Lectures

• Molecular Mechanisms of Anthracycline Cardiotoxicity (Invited Presenter) 
  Las Vegas, NV - 7/1/2014
• Structure and Function of the Cardiac Cytoskeleton (Invited Lecturer) 
  Albuquerque, NM - 5/1/2013
• Causes of Sudden Death in Young Athletes (Gregory Derringer Invited Grand Rounds Speaker) 
  Indianapolis, IN - 6/1/2012
• The Ins and Outs of the Cardiac Cytoskeleton (Invited Professor) 
  Atlanta, GA - 4/1/2012
• Causes of Sudden Death in Young Athletes 
  New Orleans, LA - 7/1/2011
• The Ins and Outs of the Cardiac Cytoskeleton 
  Detroit, MI - 6/1/2011
• The Ins and Outs of the Cardiac Cytoskeleton (Invited Lecturer) 
  New Orleans, LA - 5/1/2011
• A Day in the Life of a Cardiovascular Pathologist (Invited Lecturer) 
  Maywood, IL - 9/1/2005
• The Role of the Cytoskeleton in Ischemic Injury: New Insights into a Static Problem (Invited Symposium Speaker) 
  Mystic, CT - 6/29/2003
• Role of the Cytoskeleton in Lethal Myocyte Injury: fact or fiction? (Invited Lecturer) 
  Columbus, OH - 5/15/2002
• The Role of Heat Shock Proteins and the Cytoskeleton (Invited Symposium Speaker) 
  New Orleans, LA - 4/20/2002
• Ischemic Myocardial Injury: new insights and paradigms (Invited Lecturer) 
  Chicago, IL - 9/17/1998
• Role of MAPK in Ischemic Preconditioning in Isolated Canine Ventricular Myocytes 
  Detroit, MI - 1/1/1998
• Role of Isolated Myocytes in Ischemic Preconditioning 
  Ann Arbor, MI - 9/1/1997
• The Role of Isolated Myocytes in Ischemic Preconditioning (Invited Symposium Speaker) 
  Vancouver, British Columbia, Canada - 7/23/1997
• A Day in the Life of a Cardiovascular Pathologist; Or, Why Do We Study Ischemic Preconditioning Anyway? 
  Portland, OR - 7/14/1994
• Ischemic Preconditioning: Can a Little Ischemia be a Good Thing? 
  Portland, OR - 7/14/1994
• Catecholamines are not required for ischemic preconditioning in canine myocardium 
  Atlanta, GA - 11/1/1993
• Adenosine mimics ischemic preconditioning in its effect on ischemic myocardial metabolism-possible role of catecholamines 
  Kobe, Japan - 5/1/1992
• Effect of reversible ischemia on mitochondrial ATPase activity in canine myocardium 
  Anaheim, CA - 11/1/1991
• Join now to see all

Other

• Biology of Acute Myocardial Cell Death (Doctoral Dissertation) 
  Vander Heide RS, Northwestern University
  Chicago, IL - 1/1/1986