Skip to main content
Stephan Grupp, MD, Pediatric Hematology & Oncology, Philadelphia, PA, Children's Hospital of Philadelphia

StephanAGruppMDPhD

Pediatric Hematology & Oncology • Philadelphia, PA

Pediatric Hematologic Oncology, Pediatric Solid Tumor Oncology

Professor, Pediatrics, Perelman School of Medicine

Request Appointment

Overview of Dr. Grupp

Dr. Stephan Grupp is a pediatric hematologist/oncologist in Philadelphia, PA and is affiliated with Children's Hospital of Philadelphia. He received his medical degree from University of Cincinnati College of Medicine and has been in practice 30 years. Dr. Grupp accepts several types of health insurance, listed below. He is one of 160 doctors at Children's Hospital of Philadelphia who specialize in Pediatric Hematology & Oncology. He has more than 100 publications and over 500 citings.

Education & Training

  • Children's Hospital/Boston Medical Center
    Children's Hospital/Boston Medical CenterFellowship, Pediatric Hematology/Oncology, 1989 - 1991
  • Children's Hospital/Boston Medical Center
    Children's Hospital/Boston Medical CenterResidency, Pediatrics, 1987 - 1989
  • University of Cincinnati College of Medicine
    University of Cincinnati College of MedicineClass of 1987

Certifications & Licensure

  • PA State Medical License
    PA State Medical License 1996 - 2024
  • MA State Medical License
    MA State Medical License 1989 - 1997
  • American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

  • America's Top Doctors Castle Connolly, 2009-2014
  • America's Top Doctors for Cancer Castle Connolly, 2005-2013
  • Philadelphia Magazine Castle Connolly, 2005-2006, 2008, 2011
  • Join now to see all

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • CRISPR-Cas9 Gene Editing for Sickle Cell Disease and Β-thalassemia  
    Haydar Frangoul, Jennifer Domm, Stephan Grupp, Rupert Handgretinger, The New England Journal of Medicine
  • Genetic Mechanisms of Target Antigen Loss in CAR19 Therapy of Acute Lymphoblastic Leukemia  
    John E Levine, Muna Qayed, Stephan A Grupp, Eneida R Nemecek, Stella M Davies, Michael R Verneris, Michael Boyer, Jeffrey A Engelman, Nature
  • Induction of Resistance to Chimeric Antigen Receptor T Cell Therapy by Transduction of a Single Leukemic B Cell  
    Vijay G Bhoj, David M Barrett, Carl H June, Stephan A Grupp, David E Ambrose, Saar I Gill, Marco Ruella, Bruce L Levine, Shannon L Maude, Nature
  • Join now to see all

Abstracts/Posters

  • Identification and Validation of Predictive Biomarkers to CD19- and BCMA-Specific CAR T-Cell Responses in CAR T-Cell Precursors
    Stephan Grupp, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
  • Trends in Inpatient and Intensive Care Resource Utilization after Chimeric Antigen Receptor T Cell Therapy for Pediatric Acute Lymphoblastic Leukemia from 2012-2019
    Stephan Grupp, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
  • Single Chain Variable Fragment Linker Length Regulates CAR Biology and T Cell Efficacy
    Stephan Grupp, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
  • Join now to see all

Lectures

  • Medical Crossfire¬: Case Studies in AYA and Adult Acute Lymphoblastic Leukemia _ How the Experts Think and Treat 
    61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
  • Tisagenlecleucel Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory Children and Young Adults with Acute Lymphoblastic Leukemia (ALL): Real World E... 
    61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
  • Molecular Detection of Minimal Residual Disease Precedes Morphological Relapse and Could be Used to Identify Relapse in Pediatric and Young Adult B-Cell Acute Lymphobl... 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Join now to see all

Press Mentions

  • When Our Cells Turn Against Us
    When Our Cells Turn Against UsNovember 2nd, 2022
  • First Approved CAR T-cell Therapy Shows Continued Benefits Five Years Later
    First Approved CAR T-cell Therapy Shows Continued Benefits Five Years LaterJune 16th, 2022
  • Tribeca Film Festival to Debut Documentary Tracing the Path to Penn Medicine and Children’s Hospital of Philadelphia’s Transformative, Personalized Cancer Therapy
    Tribeca Film Festival to Debut Documentary Tracing the Path to Penn Medicine and Children’s Hospital of Philadelphia’s Transformative, Personalized Cancer TherapyJune 9th, 2022
  • Join now to see all

Grant Support

  • Determinants Of Relapse Risk After BMT For AllNational Cancer Institute2007–2011
  • Use Of Mtor Inhibitors In B Cell LeukemiaNational Cancer Institute2005–2009
  • Post Transplant T Cell Reconstitution In NeuroblastomaNational Cancer Institute2004–2005
  • Evolution Of B Precursor Leukemia In The Eu-Ret MouseNational Cancer Institute1999–2003
  • BCR Complex In B Cell Development And Allelic ExclusionNational Institute Of Allergy And Infectious Diseases1996–2000

Professional Memberships

Hospital Affiliations

Industry Relationships

  • Consultant, Pfizer
  • Consultant, Jazz
  • Consultant, Novartis

Insurance Accepted

  • Aetna Choice POS II
    Aetna HMO
    AmeriHealth Direct POS
    AmeriHealth Direct POS Value Network
    Amerihealth HMO
    AmeriHealth HMO Value Network
    AmeriHealth PPO
    AmeriHealth PPO Value Network
    BCBS Blue Card PPO
    CIGNA HMO
    CIGNA Open Access
    CIGNA PPO
    Coventry Carelink Health Plans PPO
    Great West PPO
    Horizon BCBS Direct Access
    Horizon BCBS HMO
    Horizon BCBS POS
    Horizon BCBS PPO
    Humana ChoiceCare Network PPO
    IBC Keystone HMO / POS
    IBC Personal Choice PPO
    Multiplan PPO
    Oxford Health Freedom
    Oxford Health Liberty
    QualCare HMO
    QualCare PPO
    United Healthcare - Direct Choice Plus POS
    United Healthcare - Direct Options PPO
  • Please verify your coverage with the provider's office directly when scheduling an appointment

Dr. Stephan Grupp, Dr. Stephan Grupp, MD, Dr. S Grupp, Dr. Stephan A Grupp