SusanJane(Pillsbury)KnoxMDPh.D.

Radiation Oncology • Palo Alto, CA

Academic

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Office
300 Pasteur Dr
# MC5500
Palo Alto, CA 94305
Phone+1 650-723-6171

Fax+1 650-498-5840
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Education & Training

Stanford Health Care-Sponsored Stanford UniversityResidency, Radiation Oncology, 1986 - 1990
University of California Davis HealthInternship, Internal Medicine, 1985 - 1986
Stanford University School of MedicineClass of 1985

Certifications & Licensure

CA State Medical License 1986 - 2024

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Clinical Trials

Phase 2 Study of Bexxar in Relapsed/Refractory DLCL Start of enrollment: 2004 Sep 01
Completed
Phase 2
Study of Bexxar <Tositumomab> Combined With External Beam Radiation Therapy Start of enrollment: 2007 Jan 01
Terminated
Phase 2
Pilot Ipilimumab in Stage IV Melanoma Receiving Palliative Radiation Therapy Start of enrollment: 2011 Oct 01
Completed
Phase 2
Sodium Selenite and Radiation Therapy in Treating Patients With Metastatic Cancer Start of enrollment: 2014 Jul 01
Completed
Phase 1
Palliative RT & Anti-PD-1/PD-L1 Checkpoint Blockade in Metastatic Merkel Cell Carcinoma Start of enrollment: 2019 Jul 24
Terminated
Phase 2
Study Evaluating Sodium Selenite in Combination With Abiraterone in Castrate Resistant Prostate Cancer Progressing on Abiraterone Start of enrollment: 2020 Oct 01
Withdrawn
Phase 1
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Publications & Presentations

PubMed

7 citations
ASTRO's Framework for Radiopharmaceutical Therapy Curriculum Development for Trainees.
Ana P Kiess, Robert F Hobbs, Bryan Bednarz, Susan J Knox, Ruby Meredith, Freddy E Escorcia> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Jul 15
4 citations
Basics of Physics and Radiobiology for Radiopharmaceutical Therapies.
Keara K English, Susan Knox, Stephen A Graves, Ana P Kiess> ;Practical Radiation Oncology. 2022 Jun 18
58 citations
Genomic and transcriptomic analyses of breast cancer primaries and matched metastases in AURORA, the Breast International Group (BIG) molecular screening initiative.
Philippe Aftimos, Mafalda Oliveira, Alexandre Irrthum, Debora Fumagalli, Christos Sotiriou, Einav Nili Gal-Yam, Mark E. Robson, Justin Ndozeng, Angelo Di Leo, Eva M. C...> ;Cancer Discovery. 2021 Jun 28
4 citations
Clinical Pharmacokinetics of Oral Sodium Selenite and Dosing Implications in the Treatment of Patients with Metastatic Cancer.
Priya Jayachandran, Susan J. Knox, Maria Garcia-Cremades, Radojka M. Savic> ;Drugs in R&D. 2021 Apr 17
134 citations
70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age
Martine Piccart, Laura J. van't Veer, C. Poncet, Josephine M.N. Lopes Cardozo, Suzette Delaloge, Jean-Yves Pierga, Peter Vuylsteke, Etienne Brain, Suzan Vrijaldenhoven...> ;The Lancet. Oncology. 2021 Apr 1
62 citations
A Review of Newly Diagnosed Glioblastoma.
Bryan Oronsky, Tony R. Reid, Arnold L. Oronsky, Navjot Sandhu, Susan J. Knox> ;Frontiers in Oncology. 2021 Feb 5
18 citations
The Radiobiology of Radiopharmaceuticals
Zachary S. Morris, Andrew Z. Wang, Susan J. Knox> ;Seminars in Radiation Oncology. 2021 Jan 1
36 citations
Breast conservation and axillary management after primary systemic therapy in patients with early-stage breast cancer: the Lucerne toolbox
Peter Dubsky, Katja Pinker, Fatima Cardoso, Giacomo Montagna, Mathilde Ritter, Carsten Denkert, Isabel T. Rubio, Evandro de Azambuja, Giuseppe Curigliano, Oreste Genti...> ;The Lancet. Oncology. 2021 Jan 1
4 citations
Harnessing genome-wide association studies to minimize adverse radiation-induced side effects
Cecil M. Benitez, Susan J. Knox> ;Radiation Oncology Journal. 2020 Nov 25
2 citations
Locally administered heparin-binding epidermal growth factor-like growth factor reduces radiation-induced oral mucositis in mice.
Jing Chen, Laurent A. Bekale, Kelly Khomtchouk, Anping Xia, Zhixin Cao, Shoucheng Ning, Susan J. Knox, Peter L. Santa Maria> ;Scientific Reports. 2020 Oct 15
9 citations
Desperate Times, Desperate Measures: The Case for RRx-001 in the Treatment of COVID-19.
Bryan Oronsky, Susan J. Knox, Pedro Cabrales, Arnold L. Oronsky, Tony R. Reid> ;Seminars in Oncology. 2020 Oct 1
27 citations
Knowledge gaps in oncoplastic breast surgery.
Walter P. Weber, Monica Morrow, Jana de Boniface, Andrea L. Pusic, Giacomo Montagna, Elisabeth A. Kappos, Mathilde Ritter, Martin Haug, Christian Kurzeder, Ramon Sacci...> ;The Lancet. Oncology. 2020 Aug 1
19 citations
A Prospective, Phase 1 Trial of Nivolumab, Ipilimumab, and Radiotherapy in Patients with Advanced Melanoma.
, , , , , , , , , , , , , , , , , , , , , , , > ;Clinical Cancer Research. 2020 Jul 1
92 citations
TGF-beta: a master immune regulator.
Christopher A. Larson, Bryan Oronsky, Corey A. Carter, Arnold L. Oronsky, Susan J. Knox, David J. Sher, Tony R. Reid> ;Expert Opinion on Therapeutic Targets. 2020 Apr 12
9 citations
Theoretical and practical knowledge curriculum for European Breast Surgeons.
Tibor Kovacs, Isabel T. Rubio, Christos Markopoulos, Riccardo A. Audisio, Susan J. Knox, Thorsten Kühn, Robert E. Mansel, Zoltan Matrai, Francesco Meani, Maurizio B. N...> ;European Journal of Surgical Oncology. 2020 Apr 1
40 citations
Just eat it: A review of CD47 and SIRP-α antagonism.
Bryan Oronsky, Corey A. Carter, Tony R. Reid, Franck Brinkhaus, Susan J. Knox> ;Seminars in Oncology. 2020 Apr 1
45 citations
Locally advanced rectal cancer: The past, present, and future.
Bryan Oronsky, Tony R. Reid, Christopher A. Larson, Susan J. Knox> ;Seminars in Oncology. 2020 Feb 21
8 citations
Standard Anthracycline Based Versus Docetaxel-Capecitabine in Early High Clinical and/or Genomic Risk Breast Cancer in the EORTC 10041/BIG 3-04 MINDACT Phase III Trial
Suzette Delaloge, Martine Piccart, Emiel J. Th. Rutgers, Saskia Litière, Laura J. van't Veer, Franchette W P J van den Berkmortel, Etienne Brain, Aleksandra Dudek-Peri...> ;Journal of Clinical Oncology. 2020 Feb 21
2 citations
Durability of response in metastatic melanoma patients after combined treatment with radiation therapy and ipilimumab.
Quaovi H. Sodji, Susan M. Swetter, Sunil Reddy, Susan M. Hiniker, Susan J. Knox, Paulina M. Gutkin> ;Melanoma Management. 2020 Feb 12
17 citations
Development of a biodosimeter for radiation triage using novel blood protein biomarker panels in humans and non-human primates.
Robert Balog, Bacher Rowena, Polly Y. Chang, Michael Greenstein, Songeeta Jammalamadaka, Harold S. Javitz, Susan J. Knox, Shirley Lee, Hua Lin, Thomas A. Shaler, Lei S...> ;International Journal of Radiation Biology. 2020 Jan 1
Transforming Breast Cancer Together: European elections manifesto 2019 seizing the opportunities for breast cancer patients
Fatima Cardoso, Cristian-Silviu Bușoi, Ivana Cattaneo, Donatella Decise, Antonella Cardone, Alex Filicevas, Elena Gentile, Lieve Wierinck, Susan J. Knox, Silvia Sebast...> ;Breast. 2019 Dec 1
5 citations
Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer
Susan J. Knox, Priya Jayachandran, Christine A. Keeling, Kathryn J. Stevens, Navjot Sandhu, Stacy Leanne Stamps-DeAnda, Rada M. Savic, Lei Shura, Mark K. Buyyounouski,...> ;Translational Oncology. 2019 Nov 1
63 citations
High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer.
Aizea Morales-Kastresana, Thomas Musich, Joshua A. Welsh, William G. Telford, Thorsten Demberg, James C. S. Wood, Marty Bigos, Carley D. Ross, Aliaksander Kachynski, A...> ;Journal of Extracellular Vesicles. 2019 Jun 19
4 citations
Outcomes and Characteristics of Patients Treated with Emergent Palliative Radiation Therapy.
Madeline Grade, Julie L. Koenig, Yushen Qian, Navjot Sandhu, Yufei Liu, Brandon M. Turner, Rie von Eyben, Susan J. Knox, S.A. Dudley> ;Practical Radiation Oncology. 2019 Mar 1
6 citations
Complete Response of Metastatic Melanoma to Local Radiation and Immunotherapy: 6.5 Year Follow-Up
Susan M. Hiniker, Susan M. Swetter, Sunil Reddy, Susan J. Knox, Paulina M. Gutkin> ;Cureus. 2018 Dec 12
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Press Mentions

Dose-Dependent Nuclear Delivery and Transcriptional Repression with a Cell-Penetrant MeCP2February 22nd, 2023
Stanford Medical Students Celebrate Match Day VirtuallyMarch 22nd, 2021
Eighty-Five Medical Students Meet Their MatchesMarch 15th, 2019

Grant Support

Protocol Review And Monitoring System (PRMS)National Cancer Institute2007–2009
Clinical Trial: Phase II Study Of Bexxar In Relapsed/Refractory DlclNational Center For Research Resources2008
Clinical Trial: Bexxar Combined With External Beam Radiation Therapy For PatientNational Center For Research Resources2008
Phase II Study Of Bexxar In Relapsed/Refractory DlclNational Center For Research Resources2006–2007
Anti B1 Antibody For Nonhodgkins LymphomaNational Center For Research Resources2000–2001
Phase II Multicenter Trial Of 90 Yttrium DOTA Biotin In Subjects W/ CancerNational Center For Research Resources1999–2000
Iodine Anti B1 Murine Radioimmunotherapy For Chemotherapy LymphomaNational Center For Research Resources1999–2000
Anti-B1 (MURINE) In Chemotherapy-Refractory Low Grade Nonhodgkin'S LymphomaNational Center For Research Resources1997–2000
Study Of 90 Yttrium/Dota/Biotin Localization In Advanced CancerNational Center For Research Resources1996–2000
Pivotal Phase II/III Of Murine Radioimmunotherapy For LymphomasNational Center For Research Resources1998–1999
BCL-2, Na+/K+ Atpase And Radiation Induced ApoptosisNational Cancer Institute1996–1998
Radiobiology Of Low Dose Rate RadioimmunotherapyNational Cancer Institute1994–1997
Intravenously Administered 90y-Cyi-356 In Metastatic Prostate CancerNational Center For Research Resources1996
B Cell Lymphoma With 90y-Labeled B1 (Anti-Cd20) Monoclonal AntibodyNational Center For Research Resources1996
Radiobiology Of Low-Dose Rate RadioimmunotherapyNational Cancer Institute1993