ThomasFMurrayMD

PubMed

• Design, synthesis, and opioid activity of arodyn analogs cyclized by ring-closing metathesis involving Tyr(allyl).
  Fang, W. J.,Murray, T. F.,Aldrich, J. V.> ;Bioorg. Med. Chem.. 2017 Dec 24
• Structure-Activity Relationships of the Peptide Kappa Opioid Receptor Antagonist Zyklophin.
  Joshi, A. A.,Murray, T. F.,Aldrich, J. V.> ;J. Med. Chem.. 2015 Oct 23
• Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neurons.
  Cao, Z.,Li, X.,Zou, X.,Greenwood, M.,Gerwick, W. H.,Murray, T. F.> ;Mar Drugs. 2015 Feb 13
• Detailed analysis of (-)-palmyrolide a and some synthetic derivatives as voltage-gated sodium channel antagonists.
  Mehrotra, S.,Duggan, B. M.,Tello-Aburto, R.,Newar, T. D.,Gerwick, W. H.,Murray, T. F.,Maio, W. A.> ;J. Nat. Prod.. 2014 Oct 25
• Gambierol inhibition of voltage-gated potassium channels augments spontaneous Ca2+ oscillations in cerebrocortical neurons.
  Cao, Z.,Cui, Y.,Busse, E.,Mehrotra, S.,Rainier, J. D.,Murray, T. F.> ;J. Pharmacol. Exp. Ther.. 2014 Jun 25
• Alanine Analogs of [D-Trp]CJ-15,208: Novel Opioid Activity Profiles and Prevention of Drug- and Stress-Induced Reinstatement of Cocaine-Seeking Behavior.
  Aldrich, J. V.,Senadheera, S. N.,Ross, N. C.,Reilley, K. A.,Ganno, M. L.,Eans, S. E.,Murray, T. F.,McLaughlin, J. P.> ;Br. J. Pharmacol.. 2014 Mar 05
• Credneramides A and B: Neuromodulatory Phenethylamine and Isopentylamine Derivatives of a Vinyl Chloride-Containing Fatty Acid from cf. Trichodesmium sp. nov.
  Malloy, K.L., Suyama, T.L., Engene, N., Debonsi, H., Cao, Z., Matainaho, T., Spadafora, C., Murray, T.F., Gerwick, W.H.> ;J Nat Prod. 2012 Jan 27
• Unexpected Opioid Activity Profiles of Analogues of the Novel Peptide Kappa Opioid Receptor Ligand CJ-15,208.
  Aldrich, J.V., Kulkarni, S.S., Senadheera, S.N., Ross, N.C., Reilley, K.J., Eans, S.O., Ganno, M.L., Murray, T.F., McLaughlin, J.P.> ;ChemMedChem. 2011 Sep 5
• Phylogeny-Guided Isolation of Ethyl Tumonoate A from the Marine Cyanobacterium cf. Oscillatoria margaritifera.
  Engene, N., Choi, H., Esquenazi, E., Byrum, T., Villa, F.A., Cao, Z., Murray, T.F., Dorrestein, P.C., Gerwick, L., Gerwick, W.H.> ;J Nat Prod. 2011 Aug 26
• 38 citations
  Novel opioid cyclic tetrapeptides: Trp isomers of CJ-15,208 exhibit distinct opioid receptor agonism and short-acting κ opioid receptor antagonism
  Nicolette C. Ross, Kate J. Reilley, Thomas F. Murray, Jane V. Aldrich, Jay P. McLaughlin> ;British Journal of Pharmacology. 2012 Feb 2
• Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture.
  Cao, Z., Shafer, T.J., Crofton, K.M., Gennings, C., Murray, T.F.> ;Environ Health Perspect. 2011 Sep
• Kappa-opioid receptor inhibition of calcium oscillations in spinal cord neurons.
  Kelamangalath, L., Dravid, S.M., George, J., Aldrich, J.V., Murray, T.F.> ;Mol Pharmacol. 2011 Jun
• Deletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity.
  Fang, W., Bennett, M.A., Murray, T.F., Aldrich, J.V.> ;Biopolymers. 2011
• Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons.
  Cao, Z., Shafer, T.J., Murray, T.F.> ;J Pharmacol Exp Ther. 2011 Jan
• Palmyrolide A, an unusually stabilized neuroactive macrolide from Palmyra Atoll cyanobacteria.
  Pereira, A.R., Cao, Z., Engene, N., Soria-Mercado, I.E., Murray, T.F., Gerwick, W.H.> ;Org Lett. 2010 Oct 15
• The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria.
  Choi, H., Pereira, A.R., Cao, Z., Shuman, C.F., Engene, N., Byrum, T., Matainaho, T., Murray, T.F., Mangoni, A., Gerwick, W.H.> ;J Nat Prod. 2010 Aug 27
• 28 citations
  Involvement of Caspase Activation in Azaspiracid-Induced Neurotoxicity in Neocortical Neurons
  Zhengyu Cao, Keith T. LePage, Michael O. Frederick, Kyriacos C. Nicolaou, Thomas F. Murray> ;Toxicological Sciences. 2010 Apr 1
• Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors.
  Sinha, B., Cao, Z., Murray, T.F., Aldrich, J.V.> ;J Med Chem. 2009-12-10
• The effects of C-terminal modifications on the opioid activity of [N-benzylTyr(1)]dynorphin A-(1-11) analogues.
  Patkar, K.A., Murray, T.F., Aldrich, J.V.> ;J Med Chem. 2009-11-12
• Alotamide A, a novel neuropharmacological agent from the marine cyanobacterium Lyngbya bouillonii.
  Soria-Mercado, I.E., Pereira, A., Cao, Z., Murray, T.F., Gerwick, W.H.> ;Org Lett. 2009-10-15
• Design, synthesis, and pharmacological activities of dynorphin A analogues cyclized by ring-closing metathesis.
  Fang, W., Cui, Y., Murray, T.F., Aldrich, J.V.> ;J Med Chem. 2009-09-24
• Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria.
  Pereira, A., Cao, Z., Murray, T.F., Gerwick, W.H.> ;Chem Biol. 2009-08-28
• Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons.
  George, J., Dravid, S.M., Prakash, A., Xie, J., Peterson, J., Jabba, S.V., Baden, D.G., Murray, T.F.> ;J Neurosci. 2009 Mar 11
• Dual labeled peptides as tools to study receptors: nanomolar affinity derivatives of TIPP (Tyr-Tic-Phe-Phe) containing an affinity label and biotin as probes of delta ...
  Aldrich, J.V., Kumar, V., Murray, T.F., Guang, W., Wang, J.B.> ;Bioconjug Chem. 2009-02-01
• The synthesis of DAMGO-based potential affinity labels with high mu opioid receptor affinity and the formation of cyclic O-alkyl thiocarbamates.
  Dattachowdhury, B., Murray, T.F., Aldrich, J.V.> ;Adv Exp Med Biol. 2009-01-01
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